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You should not use tolvaptan if you are allergic to it, or if:

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  • you are unable to tell that you are thirsty;
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Some medicines can cause unwanted or dangerous effects when used with tolvaptan. Your doctor may change your treatment plan if you also use:

  • nefazodone;
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  • antifungal medicine--itraconazole, ketoconazole; or
  • HIV/AIDS medication--indinavir, nelfinavir, ritonavir, saquinavir.

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  • you also take desmopressin (dDAVP), or a diuretic or "water pill";
  • you are malnourished; or
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It is not known whether tolvaptan will harm an unborn baby. Tell your doctor if you are pregnant.
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